A patient with both male and female DNA has the team stumped. Meanwhile, House starts acting nicely, raising Cuddy’s and Wilson’s suspicions that something is terribly wrong.

Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities off to Cameron, including supervising House. Cameron…

The team takes on the case of a fitness guru on an all-natural diet who collapsed while filming a video. Meanwhile, Foreman conducts Huntington’s Disease drug trials and Thirteen signs…

An ailing man suffers from blackouts and sleepwalks, leading the team to wonder if his sleepwalking is a symptom, or how the man is becoming exposed to something else. When…

In the aftermath of personal tragedy, Wilson resigns from the hospital… and from his friendship with House. Meanwhile, Thirteen struggles with her personal medical problems while helping treat an executive…

House and his team must diagnose a Jewish bride who is taken ill at her wedding. However, House is more interested in analyzing Wilson’s relationship with his new girlfriend.

House copes with a patient whose symptoms conceal a greater problem, but spends much of his time dodging Cuddy’s orders to give performance reviews, and fighting with Amber over who…

Under Cuddy’s pressure to choose his team, House gives the candidates a case of a former punk rock star who is a drug user. Whoever diagnoses the patient is going…

House finds that some of his own fellowship students will do whatever it takes, when they deal with a woman who believes she can talk to the dead.

With his diagnostic team gone, House tries to diagnose a young woman who survived an office building collapse. With the condition getting worse, Cuddy puts pressure on House to hire…

House is secretly trying to treat a fighter pilot who is a candidate for NASA’s astronaut training program. Her diagnosis will be the test to choose which ones of the…

The ex-marine that saved House’s life, in a dream he had the day before, is admitted in the hospital with symptoms resembling Gulf War Syndrome. While House is busy dealing…

It’s Valentine’s Day, and Cuddy has a blind date. Meanwhile, House leaves ER duty to take the case of a child patient named Hannah.

House takes the case of a young girl who has been diagnosed with pancreatitis. When he takes her divorced parents to court to force them to allow treatment because they…

The team encounters logistical problems while trying to run tests on a 600-pound man due to his extremely large size. Meanwhile, House spends the night in jail after being arrested…

After recovering from his gunshot wounds, House works feverishly on two cases at the same time: a paralyzed man who drove his wheelchair into a swimming pool and a woman…

When a police officer with a gunshot wound to the head and uncontrollable laughter is admitted, House and the team are baffled. When Foreman begins showing the same symptoms, they…

Foreman continues to experience the same progression of symptoms as the police officer. When he realizes he may be facing imminent death, he calls his father who comes to his…

House believes a woman is trying to kill her husband and tries to find the proof to confirm his suspicions. When Wilson moves in with House after separating from his…

With Foreman as House’s supervisor, the team must figure out if a woman who cried wolf too many times is really ill.

Andie, a 9-year-old terminal cancer patient, is brought in after suffering from a hallucinogenic episode. Wilson convinces House to take the case, but he and his team struggle to diagnose…

While a meningitis scare overwhelms the resources and staff of Princeton-Plainsboro Teaching Hospital, House zeros in on a single patient: a 12-year-old whose symptoms are similar to, but not quite…

Mr. Eko has dreams about his brother leading him somewhere. He seeks Locke’s help in finding a secret location, the “question mark.” Meanwhile, Jack and the other survivors grapple with…

When a cholera epidemic hits Hell on Wheels, Cullen must find fresh water before his workers die. Durant faces political fallout.

Durant files an injunction against Union Pacific, threatening Cullen’s position; Elam deals with a dangerous newcomer.